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Dr. Gao Zhiliang

Chinese name: 高志良
Professor, Chief Physician, Doctoral Supervisor . Infectious Diseases & Hepatology
Professor Gao Zhiliang is Director of Infectious Diseases and Deputy President of the Liver Hospital at the Third Affiliated Hospital of Sun Yat-sen University. A leading authority on viral hepatitis, liver failure and infectious disease, he has led national research and expert consensus on the functional cure of chronic hepatitis B.

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Coordinated end-to-end by Orisene

nearly 300
Peer-reviewed publications
5
Papers in Cell, Hepatology and J Hepatology
2016
Guangdong Provincial Science and Technology Award (First Class)

  • The Physician

About Dr. Gao Zhiliang

Professor Gao Zhiliang is Director of Infectious Diseases, Deputy President of the Liver Hospital and head of the infectious disease teaching and research section at the Third Affiliated Hospital of Sun Yat-sen University. He has devoted his career to viral hepatitis, liver failure and severe infectious disease, leading clinical care and research on chronic hepatitis B, hepatitis C and acute-on-chronic liver failure. His team established influential diagnostic criteria and a prognostic score for HBV-related acute-on-chronic liver failure, and he has contributed to national expert consensus on the functional cure of chronic hepatitis B. He has published nearly three hundred papers, including work in Cell and Hepatology.
1、Director of Infectious Diseases and Deputy President of the Liver Hospital at the Third Affiliated Hospital of Sun Yat-sen University
2、Head of the infectious disease teaching and research section
3、Chairman of the Infectious Disease Prevention and Control Branch of the Chinese Preventive Medicine Association
4、Recipient of the State Council Special Allowance and the title Sun Yat-sen University Famous Doctor
5、Leader of national research on HBV-related acute-on-chronic liver failure
6、Lead author of the expert consensus on functional cure of chronic hepatitis B

Dr. Gao Zhiliang ’s Three Key Areas of Expertise

Three areas of focused expertise, each supported by a deep subspecialty team, high case volumes and an English-speaking care pathway coordinated by Orisene.

Chronic hepatitis B

He diagnoses and treats chronic hepatitis B with antiviral therapy and long-term monitoring, aiming for viral suppression and functional cure and reducing the risk of cirrhosis and liver cancer for patients living with this common chronic viral infection in routine clinical practice.

Liver failure

He manages acute-on-chronic and acute liver failure with intensive medical support, artificial liver therapy and antiviral treatment, working to remove precipitating causes, protect residual liver function and improve short-term survival for patients facing these life-threatening hepatic emergencies in routine clinical practice.

Severe infectious disease

He treats severe and complicated infectious diseases, including bacterial, viral, fungal and emerging infections, integrating rapid molecular diagnosis, targeted antimicrobial therapy and intensive critical care to control infection and improve survival and outcomes for patients with severe or often hard-to-diagnose infections.

More: hepatitis C——antiviral cure; liver cirrhosis——management; fatty liver——assessment; fever of unknown origin——diagnosis; infection control——prevention

  • Clinical Practice & Publications

Selected cases, research & publications

Representative work drawn from documented clinical treatments, publicly indexed literature, and hospital project records, reflecting the depth of this physician's hands-on expertise and academic rigor.
1. ‘Hot Wave Project’: A Hospital-Based Hepatitis B Management Model in China
This study evaluated the feasibility and cost-effectiveness of a hospital-based chronic hepatitis B management model in China. By standardizing screening, antiviral therapy and long-term follow-up, the program improved linkage to care for hepatitis B patients and offers a scalable model for other regions.
2. Tenofovir vs Entecavir Plus Peginterferon for Functional Cure in HBeAg-Negative Chronic Hepatitis B
Using propensity score matching, this study compared tenofovir and entecavir combined with peginterferon alfa-2b for achieving functional cure in HBeAg-negative chronic hepatitis B patients. It provides clinical evidence to help doctors choose antiviral regimens that maximize hepatitis B surface antigen clearance.
3. APASL Clinical Practice Guidelines on Chronic Hepatitis B (2026 Update)
The Asia-Pacific clinical practice guidelines update recommendations for diagnosing and treating chronic hepatitis B infection, covering antiviral drug selection, monitoring and prevention. They support clinicians worldwide in delivering standardized, evidence-based care to patients with hepatitis B, cirrhosis and related liver disease.
4. Mesenchymal Stem Cells for Acute-on-Chronic Liver Failure
This research shows that mesenchymal stem cells ameliorate acute-on-chronic liver failure and are associated with expansion of immunoregulatory hepatic natural killer cells. The findings support cell-based therapy as a promising strategy to reduce liver injury and improve outcomes in patients with severe liver failure.
5. Portal Vein Thrombosis and Short-Term Mortality in Cirrhosis
In a global cohort, this study found that portal vein thrombosis increases short-term mortality among hospitalized patients with cirrhosis. The results help hepatologists assess prognosis, guide anticoagulation decisions and improve management of complications in patients with advanced liver disease and portal hypertension.
6. Acute-on-Chronic Liver Failure-Associated Endothelial Progenitor Cells and Survival
This study revealed that CD45-positive endothelial progenitor cells in acute-on-chronic liver failure reduce survival by promoting fatty acid oxidation in vascular endothelial cells. The mechanism offers a potential therapeutic target for clinicians treating patients with liver failure, vascular injury and poor prognosis.
  • Affiliated Hospital

Where Dr. Gao Zhiliang practices

Guangzhou

The Third Affiliated Hospital,Sun Yat-Sen University

Chinese name: 中山大学附属第三医院
The Third Affiliated Hospital of Sun Yat-sen University, a Grade-A tertiary hospital founded in 1971, excels in hepatology, neurology and immunology with 5 national key disciplines, 15 national key specialties, four campuses and nationally leading liver-disease care, serving over 12,000 daily outpatients.
Since 1971
55 years of care
2,000
Licensed beds
15
National key specialties
817
Licensed beds
View Hospital Profile
Appointments with this physician are booked through official hospital channels only, coordinated end-to-end by Orisene.
  • WHY INTERNATIONAL PATIENTS CHOOSE CHINA

Why patients travel to China for treatment

Six reasons international patients now put China on their shortlist — from internationally aligned clinical capability to the policy channels that make treatment here genuinely reachable.

Clinical capability at international standard

Chinese hospitals deliver internationally aligned protocols, performing vast volumes of advanced robotic, minimally invasive, and complex transplant surgeries annually. This massive clinical data and highly specialized workforce ensure world-class outcomes, even for rare and complex cases.

Diagnostics and treatment in days, not months

A full medical workup that typically means months of waiting elsewhere is completed in China within 48–72 hours. Imaging, labs, and multidisciplinary consultations are integrated into a single visit, allowing treatment to commence immediately.

Transparent, itemised pricing

Chinese healthcare offers legally binding, itemised cost estimates before treatment begins, eliminating hidden fees or surprise billing. Due to national centralized procurement, total expenses remain 40–70% lower than comparable care in Western Europe or North America.

Policy channels that open the door

China facilitates access through 240-hour visa-free transit and dedicated medical visa routes. Policies like the Greater Bay Area drug pathway and Boao Lecheng’s pilot zone allow designated hospitals to administer innovative therapies not yet globally approved.
  • International Patient Guide

Consulting this physician, step by step

From the first message to the follow-up after you fly home, one coordinator, no paperwork on your side.
01
Day 0
  • Share your story
    A private consultation with an Orisene advisor, by message, phone or video. Send medical records in any language. Nothing is shared with the hospital yet.
02
Days 1–3
  • Records review & matching
    Orisene translates and presents your case to the right specialist. The hospital returns a tailored care plan, with costs itemised once that plan is confirmed.
03
Days 3–7
  • Your consultation
    Appointments are booked through official hospital channels only. Your navigator accompanies every visit with real-time interpretation, so you can focus on one thing: being cared for.
04
After you fly home
  • Reports & follow-up
    Translated reports and prescriptions delivered within days, remote follow-up coordination with your physicians at home, and a standing line to your navigator.
Orisene offers English and multilingual services, a professional medical interpreter at every consultation, plus translation of your records, reports and prescriptions.

Ready to plan your consultation with Dr. Gao Zhiliang?

Send your records in any language. An Orisene advisor will reply within 2 hours, present your case to the right specialist, and return a tailored care plan with itemised costs, before anything is booked. Simple. Private. Efficient.
Contact

Confidential, permanently

Independent — no hospital commission

We never handle medical fees

Information Sources

This physician profile is compiled by the Orisene team from publicly available online sources and verified at the time of publication. Details may change, and physician availability is confirmed at the time of booking.

Disclaimer: This information is for general educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider for personal medical guidance.

Mention of any specific product, brand, or manufacturer is for informational purposes only and does not constitute an endorsement or recommendation by Dr. Gao Zhiliang.